My old friend and colleague, Professor Shosei Yoshida visited our Institute and gave an excellent seminar presentation "Spermatogenic stem cell system and its regulation in the mouse testicular niche" at SCI on April 27 and 28. Shosei is currently a full Professor at Division of Germ Cell Biology, National Institute for Basic Biology, National Institute of Natural Sciences. Shosei and I used to work together for MyoD and myogenesis in National Institute of Neuroscience, Tokyo, Japan. MyoD is a basi helix-loop-helix (bHLH) type master transcriptional factor for myogenesis. Shosei believed that a bHLH transcription factor also plays an essential role for spermatogenesis. After PCR-based screeing, he successfully identified a bHLH protein Neurogenin 3 which is an earlist transcription factor for spermatogenic stem cell. In this seminar, he intrduced spermatogenic stem cell system and presented a lot of amazing time laps imaging of spermatogenic stem cells using Neurogenin 3-GFP transgenic mice. Shosei is a young rising star in the spermatogenesis field and his great work lead several publications including Science and Developmental Cell. We were very grateful to Shosei for this trip and the marverous presentation.
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